10 Best Cities in Mexico to Open a Luxury MedSpa [With Profit Calculator]

Polanco is the “Beverly Hills of Latin America.” It serves the country’s political and business elite, plus a massive expat community. The demand is for world-class, subtle anti-aging and dermatology. Prices here are the highest in the country.

San Pedro Garza García (a municipality of Monterrey) is statistically the wealthiest city in Latin America. The residents have unlimited purchasing power and closely follow US trends. They expect Texan-style service and scale.

Cancun is the entry point for medical tourism. Patients fly in for “Mommy Makeovers” and Dental Implants. A MedSpa here thrives by offering pre/post-operative treatments (Hyperbaric Oxygen, Lymphatic Drainage) to these surgical tourists.

The busiest land border crossing in the world. Thousands of Californians cross daily for healthcare. Zona Rio is the medical district. The model here is high volume, lower cost, but extremely high revenue due to the sheer number of US patients.

Cabo San Lucas and San Jose del Cabo attract Hollywood celebrities and Silicon Valley moguls. MedSpas here are essentially extensions of Los Angeles. Stem Cell therapy and advanced bio-hacking wellness are the top niches.

Tulum attracts the “influencer” crowd. A MedSpa here cannot look clinical; it must look like a jungle retreat. Services blend shamanic rituals with modern aesthetics (e.g., “Crystal Microdermabrasion”).

Known as the “Silicon Valley of Mexico.” Guadalajara has old wealth and a massive tech sector. Puerta de Hierro is the luxury district with high-rise medical towers. The market is sophisticated and demands cutting-edge tech.

A major hub for US/Canadian retirees and LGBTQ+ tourism. The market skews older, meaning high demand for “liquid facelifts” (fillers), skin tightening, and age spot removal. The patient base is incredibly loyal.

The center of the Riviera Maya. It attracts younger tourists and digital nomads. Clinics near 5th Avenue get high walk-in traffic for Botox, fillers, and CoolSculpting. It’s a faster-paced market than Tulum.

Rated the safest city in Mexico. Mérida is experiencing a real estate boom and an influx of North American expats. The North Zone (Altabrisa) is developing world-class medical facilities. Lower costs than Cancun, high quality.